Genetics
and Genomics
List of Courses
GMS GE 701 Principles of Genetics and Genomics
This course will serve as a foundation for understanding the
heritable basis of numerous biological traits, the relationships
among genes,
and the regulation of their expression. We will focus on the
ability to use genetic systems to probe these problems, and therefore
will
heavily explore the experimental aspects of these investigations.
In addition, we will discuss the impact of the genome sequences
on the
practice of modern science. Moreover, we will use a case study
approach to investigate the rich variety of scientific insights
gained through
genetic studies. Course
Homepage, 4 credits, 1st Semester
GMS GE 702 Advanced Topics in Genetics and Genomics
The Advanced Topics course will focus on the mechanisms of biological
processes that influence the inheritance and regulation of genes.
In particular, the molecular details of genetic, epigenetic, and
genomic
processes will be discussed. Both genetic and genomic experimental
approaches to these processes will be explored. In addition, we
will discuss the possibilities of utilizing these technologies in
medical
treatments. 4 credits, 2nd Semester
GMS GE 705 Critical Thinking in Genetics and Genomics
This class is designed to chronologically follow the development
of a field of study, the cell cycle, to allow students to explore
the
logical evolution of a coherent line of scientific inquiry. The
individual meetings build on the background studies discussed in
previous meetings,
examine apparent discrepancies in experimental results, critique
the approaches employed by the authors, and consider the logical
follow-through
experiments for the results at hand. 2 credits,
2nd Semester
GMS GE 703 and 704 Genetics and Genomics Colloquium
The Genetics and Genomics Colloquium will be a highly participatory
journal club where the students will be asked to give presentations
on cutting edge research with the focus on communication skills
rather than scientific content. This approach will allow students
to become
more comfortable with public speaking while developing the skills
necessary for effective communication of scientific ideas. 4 credits
(2cr. each semester)
3rd and 4th Semesters
GMS BI 755 General Biochemistry
This course is designed to provide graduate students with a solid
foundation in biochemistry and molecular biology and also to introduce
graduate
students to critical reading of scientific papers. The overall
goal of this two-semester course is to provide a comprehensive
in-depth view of the principles, concepts, and methodology underlying
the
field
of biochemistry. The first semester lecture/session schedule
is integrated with GMS MS 753 Cell Biology so students study basic
biochemical
concepts
within the context of the cell and its various compartments.
Emphasis is placed on experimental approaches to the characterization
of
macromolecular and molecular structure function relationships and
the regulation of
gene expression. 4 credits, 1st Semester
GMS MS 753 Cell Biology
This course involves the study of cell membranes, receptors,
cytoplasmic organelles, cell motility, cell cycle, extracellular
matrix-cellular
interactions, fertilization, embryogenesis, and cell differentiation.
4 credits, 1st Semester
GMS BI 782 Molecular Biology
Advanced molecular biology using the current literature as a source
of information. Emphasis is placed on relevant research techniques.
Topics include structure and function of nucleic acids, recombinant
DNA research, molecular biology of important cellular processes,
and regulation of gene expression emphasizing control mechanisms
in eukaryotic
cells. 4 credits, 1st Semester
Electives:
(Six credits, Second Year)
GMS MM 703 Cancer Biology and Genetics
The course will begin with an historical perspective; review the
major mechanistic pathways relating to oncogenes, antioncogenes,
cell cycle
control, genome instability, repair, and apoptosis; discuss standard
and experimental genomic principles of cancer treatment and diagnosis;
and conclude with a discussion of cancer epidemiology and health
policy issues that affect all basic translational cancer research.
, 2 credits
ENG BE 700 Mechanisms and Models of Cellular
Regulation
Regulatory and control processes in cells are presented from a genetic
and biochemical network perspective. Systems analysis of networks
include logical (Boolean), deterministic (differential equations),
and stochastic
approaches. Case studies of gene regulatory networks as well as
metabolic, signaling, cell survival, proliferation and death pathways
are discussed.
Existing modeling platforms of systems biology and bioinformatic
pathways databases are introduced. Course
Homepage 4 credits
Additional electives offered by various Departments at BUSM are also
approved including:
Fall Semester-
GMS MS 781 Human
Genetics, Course Homepage 4
credits
GMS MM 701 Genetics and Epidemiology of Disease,
2 credits
GMS MI 713 Comprehensive Immunology,
4 credits
GMS MM 703 Cancer
Biology and Genetics, 2 credits
GMS BI 783 Protein
Structure and Function, 2 credits
GMS BI 787 Molecular
Mechanisms of Growth and Development, 2
credits
GMS BI 790 Receptors
and Signal Transduction, 2
credits
ENG BE 561 DNA
and Protein Sequence Analysis, 4
credits
Spring Semester-
GMS BI 776 Gene
Targeting in Transgenic Mice, 2
credits
GMS BI 786 Biochemical
Mechanisms of Aging, 2
credits
GMS BI 793 Mass
Spectrometry and Functional Genomics, 2
credits
GMS MS 700 Elementary
Biostatistics, 2 credits
GMS MI 714 Genetics
of Microorganisms, 4 credits
GMS MI 717 Growth
Control and Cell Transformation, 4
credits
GMS AN 804 Teaching
Methods in the Biomedical Sciences, 2
credits
ENG BE 700 Mechanisms
and Models of Cellular Regulation, 4
credits
MET AD 893 Technology
Commercialization: From Lab to Market, 4
credits
