Pharmacology
&
Experimental Therapeutics
List of Courses
GMS
PM 700
Molecular Neurobiology and Pharmacology
Prereq: consent of instructor. Examines a spectrum of topics
ranging from the regulation of gene expression in the nervous system
to the structure and function of receptors and ion channels. Emphasis
is placed on theoretical foundations of pharmacological methods in neurobiology.
Farb, staff. 4 cr, 2nd sem.
GMS
PM 710 Laboratory Techniques in Modern
Pharmacology
Prereq: consent of instructor. Supervised laboratory rotation
emphasizing modern research techniques in molecular, cellular, and behavioral
pharmacology. Problems of collection, summary, and interpretation of
data are addressed. Russek, staff. 2 cr, either sem.
GMS
PM 720 General Medical Pharmacology
Prereq: GMS BI 751, GMS PH 740, GMS MS 703 or equivalent, and consent
of instructor. Pharmacologic principles and properties of chemical
agents of interest to human medicine are presented in lectures and workshops.
Lectures provide a complete survey of drug classes affecting organ systems
such as the nervous system, as well as antimicrobial and cancer chemotherapeutic
agents. Workshops emphasize interpretation of pharmacologic data and
patient-oriented problem solving. Walsh, staff. 8 cr, 1st sem.
GMS
PM 730 Introduction to Medical Pharmacology
Prereq: Premedical courses in the sciences. Principles of pharmacology
are covered and several major classes of therapeutic agents, with attention
to their mechanisms of action. Issues of current and future concern
in medical pharmacology are addressed including problems of drug abuse,
the ethics of human experimentation, the pricing of new drugs, and new
biotechnological approaches to drug design and development. Walsh,
staff. 4 cr, 1st sem.
GMS
PM 800 Advanced General Pharmacology
Prereq: consent of instructor. Lectures and discussions on the
major classes of pharmacologic agents, with special attention to molecular,
cellular, and physiological mechanisms of therapeutic effects. Yamamoto,
staff. 2 cr, 1st sem.
GMS
PM 810 Current Topics in Pharmacological
Sciences
Prereq: consent of instructor. Given in conjunction with the
weekly seminar program of the department. Students present and discuss
research papers with the visiting scientist working on the cutting edge
of pharmacology. Leeman.
2
cr, 2nd sem.
GMS
PM 820 Behavioral Pharmacology
Prereq: consent of instructor. Emphasizes pharmacologic basis
of drug action in the central nervous system, stressing aspects of behavioral
pharmacology and problems of drug addiction. Pierce. 2 cr, 1st
sem.
GMS
PM 830 Principles of Pharmacokinetics
Prereq: consent of instructor. Lectures and discussion on basic
factors determining absorption, distribution, biotransformation, and
excretion of drugs. Includes methods of analysis and interpretation
of pharmacokinetic data. Walsh. 2 cr, 2nd sem.
GMS
PM 840 Neuroendocrine Pharmacology
Prereq: consent of instructor. Covers the basic principles of
neuroendocrinology with special emphasis on pharmacologic aspects. Topics
include the biochemistry, physiology, and pharmacology of the neural
hormones, as well as selected topics in the interrelationship of neurohormones
and the immune system. Leeman. 2 cr, 1st sem.
GMS
PM 850 Biochemical Aspects of Neurotransmitters
and Chemical Mediators
Prereq: consent of instructor. Lectures and discussions on biosynthesis,
inactivation, receptors, and signaling mechanisms of neurotransmitters
and chemical mediators including GABA, glutamate, acetylcholine, catecholamines,
purines, peptides, prostaglandins, and histamines. Yamamoto.
2 cr, 2nd sem.
GMS
PM 860 Electrophysiology and Pharmacology
of the Synapse
Prereq: GMS PM 700, MS 703, PH 742, or consent of instructor. Examines
electrophysiologic, pharmacologic, and optical studies of transmission
at central synapses. Lectures and discussions based on research publications
will cover basic and more novel concepts in synaptic transmission. Emphasis
will be placed on critical evaluation of journal articles and on scientific
writing skills. Staff. 2 cr, 2nd sem.
GMS
PM 880 Gene Regulation and Pharmacology
Prereq: consent of instructor. Focuses on fundamental aspects
of gene control with emphasis on the dual role of RNA as both an informational
and a catalytic molecule. Topics range from discussions of gene transcription
and RNA splicing, to discussions of ribozymes as therapeutic agents.
The relevance of these topics to the understanding, and potential treatment,
of disorders that result from altered patterns of gene expression is
stressed. Ozer, Russek. 2 cr, 2nd sem.
GMS
PM 931, 932 Research in Pharmacology
Variable cr.
